Similarities in coagulation for turophiles and clottologists

‘The leperous distilment, whose effect Holds such an enmity with blood of man…. …And a sudden vigor doth posset And curd, like eager droppings into milk, The thin and wholesome blood’ Curdling milk is the process by which various proteins in join to form clumps. This assemblage can be imagined mimic thrombus formation where clotting ‘join’ clot. To explain similarities between cheese clots, it would useful look at four-factor classic theory coagulation proposed Paul Morawitz early 1900s.4 four factors this model were fibrinogen (I), prothrombin (II), calcium (III) thrombokinase (IV; now called thromboplastin).4 suggested that behaved as enzyme presence was responsible for converting thrombin, then converts fibrin.5 A similar occurs during making wherein enzymatic production, having been discovered serendipitously. An Arabian legend mentions travelling merchant named Kanana who his travels desert.6 He had stored containers made from stomachs animals, contain rennet. Rennet causes coagulate action protease, chymosin (vis-à-vis thrombokinase). cleaves casein separates curds whey (the liquid part). curd likened clot serum coagulation. What about cheese-making coagulation? brings us Andrew Buchanan coagulation-related discoveries are not widely known. lived era physiologists chemists thought spontaneous when he reflected: ‘so far considered coagulability characteristic property fibrin, distinguished albumin casein; ……. My experiments,..., shew fibrin has least tendency deposit itself spontaneously coagulum: that, casein, often coagulates under influence suitable reagents’.7 Knowing lack spontaneity formation, went on create forming substance, termed ‘washed blood-clot’, mixing one-part six 10 parts water.7, 8 following day, mixture filtered through coarse linen cloth, substance left cloth washed water. ‘A small portion could cause rapidly itself’.7 fascinating remark context was: power, coagulating less remarkable than rennet indeed, may aptly compared’.7 His use compared cheesecloth some styles making, used remove assists holding together. In summary, there interesting linked word ‘coagulation’. However, although ‘Milk’s Leap Towards Immortality’ (a known quote television personality, Clifton Fadiman), always step towards imperishability. None.